Last decade (2000-2009 ) characterized by the continuing large epidemics and outbreaks of cholera in Africa and Asia, puts the infection from endemic foci formed in these continents to the neighboring countries, as well as in the United States, Canada, Europe and Australia with Oceania.

During this period, according to official WHO data recorded 1543399 cholera patients with lesions of every year from 45 to 60 countries. Extrapolation forecasting long-term incidence of cholera in the world on a straight trend line for 2010-2011 indicates that the tendency for growth (about 1961).